产品货号：
Z26789
中文名称：
SIRP alpha/SIRPA抗体
英文名称：
Anti-SIRP alpha/SIRPA Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIRP alpha/SIRPA Antibody |
| 指标别名 | BIT;CD172A;Inhibitory receptor SHPS 1;Macrophage fusion receptor;MFR;MYD 1;MyD 1 antigen;MYD1;P84;PTPNS1;SHP substrate 1;SHPS 1;SHPS1;SIRP;SIRP alpha;SIRP ALPHA 1;Sirp alpha 2;Sirp alpha 3;SIRPA;SIRPalpha;SIRPalpha2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC |
| 基因名称 | SIRPA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SIRP alpha antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human SIRP alpha 1.The immunogen is located within the last 50 amino acids of SIRP alpha. |
| 计算分子量 | 55kDa |
| 成分 | SIRP alpha Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SIRP alpha Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis,differentiation,migration,survival,transformation or death.SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors.A novel SHP-2 associated glycoprotein was recently cloned from human,rat,mouse and cattle by several labs and was designated SIRPalpha,SHPS-1,MyD-1,BIT and p84.SIRPalpha is a new gene family containing at least fifteen members.SIRPalpha is a substrate of many activated tyrosine kinases such as insulin receptor,EGFR,PDGFR and src,and a specific docking protein for SHP-2.SIRPalpha has regulatory effects on cellular responses induced by serum,growth factors,insulin,oncogenes,growth hormones and cell adhesion and plays a general role in different physiological and pathological processes. |
| Uniprot ID | P78324 |
| 基因名全称 | Signal-regulatory protein alpha |
| 蛋白名全称 | Signal-regulatory protein alpha |
| 推荐稀释比 | SIRP alpha antibody can be used for Western blot at 0.5 ～ 1μg/mL.75 ～ 110kDa bands should be detected.Antibody can also be used for immunocytochemistry starting at 1μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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